Biomedical Data Science & Analytics

Integrating machine learning and multi-omics to identify key SUMOylation molecular signature in sarcoma

DOI: 10.71321/lcflx.00001

Jinhao Cheng, Zhitao He, Juehua Jing, Yuyao Liu, Haoxue Zhang

e88 PDF Full Text

A Mendelian randomization study investigating the causal relationship between 35 blood and urine metabolite biomarkers and postmenopausal osteoporosis

DOI: 10.71321/ktnt2936

Yimin Liu, Runtong Liu, Yuhan Zhao, Yongheng Wang, Xiaoli Hou, Fuyuan Cao, Xinhao Fan, Lei Xing, Binbin An, Faming Tian

e111 PDF Full Text

Deciphering the multifaceted significance of MPZL2 in pancreatic cancer via in-depth bioinformatics analyses

DOI: 10.71321/75r4yp80

Ziye Zhuang, Lai Jiang, Yubin Feng, Yuan Kang, Hao Chi

e117 PDF Full Text

Clinical Decision Support & AI in Medicine

Research on the Impact of PiCCO-guided Precise Fluid Resuscitation on Hemodynamics and Organ Perfusion in Patients with Extremely Severe Burns

DOI: 10.71321/7gk65202

Lulu Jiang, Zijian Zhang, Yindong Wu, Youxin Yu, Yi Hu, Delin Hu

e101 PDF Full Text

Methods, Algorithms & Software

ATPexGen: ATP-induced cell death database

DOI: 10.71321/rwcd3q57

Wei Wang, Yanfei Wang, Xuqiang Yang, Rui Zhao, Doblin Sandai, Zhijing Song, Haoling Zhang

e90 PDF Full Text

Medical Informatics Cases, Reviews & Applications

Inflammatory Responses of High Mobility Group Protein B1 in Disease: Current Trends, Novel Insights, and Challenges

DOI: 10.71321/4an4s550

Yan Huang, Lina Qin, Guangtao Liang, Peng Dong, Xiaoya Xiong, Yantong Wan

e106 PDF Full Text

Global research status and hotspots of squamous cell carcinoma endothelial cells in the last 20 years: A bibliometric analysis

DOI: 10.71321/m8qh8d83

Jiang Li, Zhe Dong, Wei Ren, Sibo Bi, Tianwen Gao, Junyi Zhou

e114 PDF Full Text

Biomedical Data Science & Analytics

Genetic Risk Mapping and Insights into Esophageal Adenocarcinoma Development

DOI: 10.71321/mczdpt96

Wenjie Li

e130 PDF Full Text

Sphingomyelin mediates the association between natural killer cell receptor 2B4 (CD244) and head and neck cancer

DOI: 10.71321/cdx1k098

Boxuan Han, Shaokun Liu

e145 PDF Full Text

Clinical Decision Support & AI in Medicine

Development and Validation of Nomogram for Predicting the Risk of Community-acquired Pneumonia after Kidney Transplantation of Deceased Donors

DOI: 10.71321/kbfm1398

Dongsheng Li, Mo Yang, Ji Zhang, Jinbiao Zhong, Handong Ding, Wei Chen, Jiashan Pan, Guiyi Liao

e115 PDF Full Text

Digital Health & Public Health Informatics

Impact of heavy metals on allostatic load in adults: a NHANES study

DOI: 10.71321/3b9xjm29

Yiyin Rong, Shenglin Luo, Cong Wu, Haozhe Huang, Ming Chen, Xingyu Liu, Shaobo Wu

e133 PDF Full Text

Correlation Analysis between Spontaneous Nystagmus Characteristics and Semicircular Canal Dysfunction in Patients with Vestibular Neuritis: A Quantitative Study Using Electronystagmography and Video Head Impulse Test

DOI: 10.71321/ceerva81

Jun Cao, Jingye Wang

e149 PDF Full Text

Medical Informatics Cases, Reviews & Applications

Exploring Long Noncoding RNAs and Ferroptosis in Cancer Progression

DOI: 10.71321/jjrzya36

Qiulian Mo, Yunshan Qiu, Yuni Liang, Qiaoying Wei, Xuefei Fan, Wenpeng Pang

e128 PDF Full Text

Effects and Mechanisms of Parental Electromagnetic Radiation Exposure on Offspring Health: A Narrative Review

DOI: 10.71321/24d64c27

Xiwen Yang, Jiaming Guo, Hongli Yan

e132 PDF Full Text

Precision Medicine Informatics

Research Progress of Epigenetic Regulation in Stroke Treatment

DOI: 10.71321/y2sx8j49

Tiancai Yang, Lei Feng

e124 PDF Full Text

Unraveling the Role of Anoikis in Non-Alcoholic Fatty Liver Disease Progression and Immune Cell Infiltration

DOI: 10.71321/p63ws623

Yuming Wang, Xinqiang Li, Jijun Shan, Ruidong Ding, Jinzhen Cai

e129 PDF Full Text

Biomedical Data Science & Analytics

Causal Relationship between Chronic Gastritis and Sleep Apnea Syndrome: A Bidirectional and Two-step Mendelian Randomization Study

DOI: 10.71321/zrtsfk74

Ziyan Zhao, Yanyu Zhu, Chang You, Yan Wang, Tianchi Zhuang, Yingqi Yang

e180 PDF Full Text

Clinical Decision Support & AI in Medicine

Clinical Analysis of Children with Mixed Macrolide-Resistant Mycoplasma Pneumoniae Infection

DOI: 10.71321/3xpc7j52

Zhengyuan Wang, Yuanhong Xu

e131 PDF Full Text

Digital Health & Public Health Informatics

Tinnitus and Risk of Mortality in Normal-Hearing U.S. Adults: A Weighted Study Adjusted for Covariate Balance

DOI: 10.71321/2eyyzr69

Yuchen Zhang, Yanqiang Zhang, Ziyue Fu, Chuanlu Shen, Kaile Wu, Yehai Liu

e225 PDF Full Text

Medical Informatics Cases, Reviews & Applications

Transthoracic pulmonary artery radiofrequency denervation (TPARFD) concomitantly with cardiac operations in adult atrial septal defect with pulmonary arterial hypertension: case report

DOI: 10.71321/89fykb91

Wenpeng Dong, Shenglin Ge, Min Lin, Weida Zhang

e135 PDF Full Text Video

Dynamic Evolution of Hyperplastic Polyps in the Setting of Autoimmune Gastritis: An In-Depth Interpretation of Gastrin-Driven Patho-mechanisms in a Case

DOI: 10.71321/19f3bp17

Yimin Song, Jianing Yan

e168 PDF Full Text

Precision Medicine Informatics

Mapping heterogeneous molecular subtypes of circadian misalignment underlying lung adenocarcinoma risk

DOI: 10.71321/fy14v342

Ruhao Wu, Kaisaierjiang Kadier, Shuai Xu, Peiyu Yuan, Yu Yang, Pengyuan Xu, Xufeng Huang, Shujing Zhou, Song-Bin Guo, Haonan Zhang, Shiqian Zhang, Chaoyang Yu, Teng Li, Ge Zhang

e137 PDF Full Text

The role of IL-17 family in the process of pulmonary fibrosis

DOI: 10.71321/tg620c27

Ge Zhou, Amin Li, Ruikai Wang

e217 PDF Full Text

Biomedical Data Science & Analytics

Exploring the Causal Relationship Between Plasma Proteins and Systemic Lupus Erythematosus: A Mendelian Randomization Study

DOI: 10.71321/ma96k735

Xinzhen Zhao, Yinying Chai, Qianran Hong, Yuxuan Song, Yibo He

e246 PDF Full Text

Causal Relationships between 1400 Serum Metabolite Traits, 179 Plasma Lipids, and Hemorrhoids: A Mendelian Randomization Study and Meta-analysis

DOI: 10.71321/8s70we60

Lu Hu, Danyang Wang, Chang You, Ziyan Zhao, Wanlin Zheng, Luyao Wang, Yutong Li, Liangzhe Dai, Hongkai Yu

e202 PDF Full Text

Clinical Decision Support & AI in Medicine

Mendelian Randomization Reveals Height as a Risk Factor and Potential Therapeutic Target for Testicular Cancer

DOI: 10.71321/sqcqnh24

Yuanbo Xu, Jieyu Xiong, Yikun Wu, Yuanlin Wang, Hua Shi, Shuxiong Xu, Yuangao Xu

e273 PDF Full Text

Digital Health & Public Health Informatics

Forearm necrotizing fasciitis caused by freshwater fish in an immunocompromised patient with rheumatoid arthritis for 20 years: a case report and review of the literature

DOI: 10.71321/t6symt70

Zhengnan Zhao, Peng Wang, Lei Ma, Yang Wang, Jiaping Guo, Chenglong Yao, Zefan Sun, Xiu Wang, Jiabao Yang

e204 PDF Full Text

The early stage of the COVID-19 Pandemic's Psychological Footprint: A Study on the Surge of Mental Health Concerns in China as Reflected by Baidu Index

DOI: 10.71321/62xm7s05

Nana Meng, Yuan Chen, Danna Zhao, Dingtao Hu

e219 PDF Full Text

Medical Knowledge Intelligence

Do open access articles have a citation advantage? — a research based on European Urology Family

DOI: 10.71321/xpg76d58

Jincong Li, Shuangying Zhang, Ruimeng Yue, Chengxiang Tian, Yuyao Jian, Rui Chen, Yang Liu, Yun Peng, Yuxuan Song

e262 PDF Full Text

Precision Medicine Informatics

Multidimensional Roles of EZH2 and Its Therapeutic Potential in Cancer Therapy

DOI: 10.71321/q01vae55

Hui Yin, Jinna Tan, Jiaqian He, Mingfen Li, Hongsheng Lin

e252 PDF Full Text

Biomedical Data Science & Analytics

Exploring New Therapeutic Targets for Myasthenia Gravis: A Plasma and Cerebrospinal Fluid Proteomics Mendelian Randomization Study

DOI: 10.71321/ybarkw62

Hongmei Miao, Yinying Chai, Qianran Hong, Yuxuan Song, Yibo He

e249 PDF Full Text

Construction of prognostic model and tumor microenvironment landscape based on cuproptosis-related subtypes in melanoma

DOI: 10.71321/vxy0xd87

Zishen Xia, Nan Gao, Jianwen Wang, Lizhao Yan, Cong Ma, Kangwei Wang, Yuxiong Weng

e214 PDF Full Text

Clinical Decision Support & AI in Medicine

New Insights into Influenza Virus–Host Interactions, Immune Responses, and Vaccine Development at Single-Cell Resolution

DOI: 10.71321/dz9d7b09

Xingting Li, Lingxi Gao

e259 PDF Full Text

Digital Health & Public Health Informatics

The Recent Changing Global Landscape of Cancer

DOI: 10.71321/e37ss652

Ilayda Karsidag, Hengrui Liu

e312 PDF Full Text

Trends and Cross-Country Inequalities of Melanoma and Non-Melanoma Skin Cancer from 1990 to 2021 and Predictive Trends from 2022 to 2044: A Global Burden of Disease Study

DOI: 10.71321/pykzbr95

Zhan Li, Yuqin Tang, Yuan Chen, Yuxin Wang, Yaping Feng, Yue Li, Yingying Yu, Mingyi Zhang, Fang Wang

e284 PDF Full Text

Medical Informatics Cases, Reviews & Applications

The cGAS-STING Pathway: Insights into Regulatory Mechanisms, Disease Dysregulation, and Therapeutic Development

DOI: 10.71321/dr57c347

Yunyong Wang, Xiaohang Lu, Jinna Tan, Jiaqian He, Hui Yin, Peipei Chen, Hemeng Wu, Yuzhen Luo, Mingfen Li

e300 PDF Full Text

Biomedical Data Science & Analytics

Transcription Factors as Early Diagnostic Biomarkers for Chronic Kidney Disease: A Comprehensive Analysis

DOI: 10.71321/1pe9g186

Wei Zhou, Qingqing Jia, Shujun Wu, Hanyan Meng, Xinyu Wang, Mingzhu Jiang, Jianhua Mao

e127 PDF Full Text

Clinical Decision Support & AI in Medicine

Artificial Intelligence–Enabled Dissection of Regulatory T Cells in the Tumor Immune Microenvironment: From Mechanistic Insight to Population-Scale Inference

DOI: 10.71321/s2yhxp11

Xuexue Hao, Muwei Li, Tao Xiong, Xiaoqiang Liu

e342 PDF Full Text

Digital Health & Public Health Informatics

Risk Factors of Reactive Cutaneous Capillary Endothelial Proliferation in Advanced Non-small Cell Lung Cancer Treated with Camrelizumab

DOI: 10.71321/ncbcdv45

Liuning Wang, Shuxing Chen, Siyu Sun, Wenyi Li, Congjun Zhang

e350 PDF Full Text

High-risk Factors and a Nomogram Prediction Model for Pulmonary Fungal Infection in Elderly Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

DOI: 10.71321/d3zf3339

Tiantian Zhang, Siyu Sun, Yingying Zhu

e327 PDF Full Text

Medical Informatics Cases, Reviews & Applications

Gut Microbiota and Hypertension: From Pathogenesis to Therapeutic Potential

DOI: 10.71321/w9jjqk66

Haitao Yang, Jingkun Liu

e303 PDF Full Text

Regulatory T Cells in Precision Immunotherapy: Mechanistic Insights and Translational Advances of Low-dose Interleukin-2

DOI: 10.71321/xk8wzt47

Ruiling Feng, Bo Huang, Xia Zhang, Jing He

e307 PDF Full Text

Precision Medicine Informatics

Puerarin Inhibits Gastric Cancer Cell Proliferation by Blocking the G2/M Phase Transition

DOI: 10.71321/zf32x172

Jianye Han, Weiwei Yuan

e301 PDF Full Text